Lactic dehydrogenase activity of serum in mice with transplantable leukemia.

نویسندگان

  • C FRIEND
  • F WROBLEWSKI
چکیده

Reports Enzymatic Oxidation of Glucose to Glucosone in a Red Alga: R. C. Bean and W. Z. Hassid ...................................... "Clock" Controlled Activity Rhythms in the Fruit Fly: S. K. de F. Roberts Hardness of Substances in the Ideal State: A. E. Newkirk ................ Lactic Dehydrogenase Activity of Serum in Mice with Transplantable Leukemia: C. Friend and F. Wro'blewski ............................ Evolution of Respiratory Enzyme System during Germination .of Bacillus subtilis: Y. Hachisuka et al................................. Rapid Ion-Exchange Method for Determining Total Fluoride in Impure KF * HF: F. A. Koehler and W. A. Levier .................... Ratio of Ionium to Uranium in Coral Limestone: J. W. Barnes, E. J. Lang, H. A. Potratz ............................. Flotational Lipoproteins Exracted from Human Atherosclerotic Aortas: M. Hanig, J. R. Shainoff, A. D. Lowy, Jr................... Consistent Set of Running Times: M. H. Lietzke ........................ Comparison of Pinch-Caliper and X-ray Measurements of Skin plus Subcutaneous Fat: S. M. Garn ................................ Chamber for Microelectrode Studies in the Cerebral Cortex: P. W. Davies Elevation, of Platelets in Mid-Cycle: an Indication of Ovulation: H. Pepper and S. Lindsay ......................................... Multiple Glaciation since the Ice Age: A. E. Harrison .................... Penetration of Slow Electrons through Spore Walls of Bacillus megaterium: H. P. Knauss ................................

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Serum lactic dehydrogenase activity in mice with transplantable leukemia.

Previous studies in man have shown that an elevated level of serum lactic dehydrogenase (SLDH) occurs in many individuals with neoplastic disease (1,3). This elevation has been noted most consistently in patients with untreated leu kemia (1). In an extension of these studies, experi ments were undertaken to determine the level of SLDH in the blood of AKR mice before, and at various intervals af...

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Etiologic role of lactic dehydrogenase virus infection in an age-dependent neuroparalytic disease in C58 mice.

Lactic dehydrogenase virus (LDV) associated with transplantable line Ib lymphocytic leukemia in C58iWm mice, K36 lymphocytic leukemia in AKRiJ mice, and the Gardner lymphosarcoma in C3HIHeJ mice elicited a fatal neuroparalytic disease when injected ip into 7to g-month-old X-irradiated indicator C58 mice. LDV associated with the WEHI-3B line of transplantable myelomonocytic leukemia or the Hardi...

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Effect of lactic dehydrogenase virus infection on tumor induction and tumor growth.

The ubiquitous nononcogenic lactic dehydrogenase RNA virus (LDV) is one of the most common contaminants of transplantable tumors and oncogenic viral preparations. This association of LDV with a large variety of murine tumors and the known effect of LDV infection on immune competence may suggest the existence of a possible etiological relationship between the virus and murine tumors. We have fou...

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Evaluation of Glutamate Dehydrogenase Activity and Insulin Secretion in Mice Exposed to Dexamethasone

Background and Aims: Diabetes is one of the most important endocrine disrupters and is associated with various hormones, including those that can lead to diabetes. Glucocorticoid use may lead to insulin resistance. Dexamethasone is one of these glucocorticoid compounds. Glutamate dehydrogenase plays a key role in the production of glutamate in the secretion of insulin. Based on these hormonal i...

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Correlation of serum lactic dehydrogenase activity with the clinical status of patients with cancer, lymphomas, and the leukemias.

The original observations of Hill and Levi (5) that serum from many individuals with neoplastic disease exhibited an elevated level of lactic dehydrogenase (LDH) activity demanded further study of the level of the serum enzyme in health and disease (1). Significant amounts of LDH ac tivity have been found in transplanted tumors (7, 10). Furthermore, the serum LDH activity of mice increases prom...

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عنوان ژورنال:
  • Science

دوره 124 3213  شماره 

صفحات  -

تاریخ انتشار 1956